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1 Learning from the past to promote present and future healthy trajectories Over the past decades, a wealth of findings rekindled the interest in the older concept of Epigenetics (Above the genome), which was coined by Conrad Waddington to explain how identical genotypes could unfold different phenotypes as development proceeds [7, 8]

GLP-1 RAs are often prescribed in combination with other medication to treat type 2 diabetes

3 Mitochondrial modulation of epigenetic function There is an increasing recognition that mitochondrial metabolism can significantly affect epigenetic function and the corresponding brain plasticity

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