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Adigun RA, Malan FP, Balogun MO, October N (2022) Rational optimization of dihydropyrimidinonequinoline hybrids as Plasmodium falciparum glutathione reductase inhibitors
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The primary outcomes measured were the change in the KCCQ-CSS and the percentage change in body weight from baseline to week 52
In addition, a uniform and statistically significant reduction in ALT, as a marker of hepatocyte damage, was observed in all combination groups 59
If approved, elecoglipron could become the third major oral GLP-1 option targeting obesity, joining Novo Nordisk's oral semaglutide (often referred to as Oral Wegovy) and Eli Lilly's investigational orforglipron, which recently received the brand name Foundayo
Keep tirzepatide in its original carton to shield it from light and sudden changes in temperature
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