Over 250 patients underwent metabolomics and lipidomic investigations, which revealed that unlike the baseline and placebo, tirzepatide, taken over 26 weeks, significantly impacted a group of lipids and metabolites like 3-hydroxybutyrate reduced branched-chain ketoacids (BCKA), branched-chain amino acids (BCAA), and direct catabolic products linked with obesity and insulin resistance
PMID: 39798341 Adv Healthc Mater Microneedle Assisted Melittin-Chondroitin Sulfate Administration for the Transdermal Therapy of Rheumatoid Arthritis
Additional Health Benefits: Improved blood sugar control, significant weight loss, cardiovascular benefits, metabolic impact
doi: 10.1016/j.trre.2016.09.001 13 MalvezziPRostaingL
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He says hes fairly fit, with no desire to lose weight