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Ipamorelin, for instance, stimulates growth hormone release excellent for preserving lean mass but it doesn't directly suppress appetite or accelerate lipolysis the way GLP-1 receptor agonists do
"Effects of insulin-like growth factor-I and LR3IGF-I on regional blood flow in normal rats." Journal of Endocrinology 155.2(1997):351-358
M.GattaniS.MisraM.et al (2025)
Also fit in little moments of unstructured activity: Take the stairs, walk to the store, stand up when chatting on the phone, and do some dance moves or squats while waiting for the pasta water to boil
When appetite drops sharply, protein intake usually drops with it, and the body pulls from muscle to cover the shortfall
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