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Was the change clinically meaningful

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Published research data is limited regarding long-term human side effects

NAD(+)-linked alcohol dehydrogenase 1 regulates methylglyoxal concentration in Candida [PMID: 24607541] Laboratory literature summary: NAD(+)-linked alcohol dehydrogenase 1 regulates methylglyoxal concentration in Candida albicans

Enzyme stability: Resists degradation by pepsin, trypsin, and other digestive enzymes

This becomes particularly important for athletes following rigorous training schedules or participating in multi-day events