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Table 2 gives an overview on the cardiovascular safety data of the DPP-4 inhibitors alogliptin, linagliptin, saxagliptin, and sitagliptin
Additionally, severe, persistent abdominal pain radiating to the back, especially if accompanied by vomiting, requires urgent medical attention as it may indicate pancreatitis, a rare but serious side effect of GLP-1 receptor agonists
Lower doses of FDA-approved GLP-1 medications may be used safely when prescribed and monitored by a clinician
General guideline: Losing more than 1% of body weight per week significantly increases the risk of lean mass loss
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