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10.1007/978-3-319-66682-2_10 Glutathione in Plant Growth, Development, and Stress Tolerance 25 CogganM.FlanaganJ
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Moreover, Ripk3 is dispensable for TNF-mediated arthritis, yet it is required for synovitis in mice with mesenchymal-specific IKK2 deletion, clearly showing that TNFR1-IKK2-Ripk-mixed-lineage kinase domain-like (MLKL) signalling pathway orchestrates arthritogenic and death responses in synovial fibroblasts and that combinatorial inhibition of nuclear factor kappa beta (NF-B) and MLKL/RIPKs may offer a therapeutic potential [26]
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