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Indeed, accumulating evidence based on preclinical studies has identified ERK5 activation as a mediator of resistance to vemurafenib (BRAFi) and trametinib (MEKi) [54], and therefore, the combined targeting of ERK5 and ERK1/2 pathways results in better outcomes [55]

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The authors found that rats fed with strictinin had a greater laxative effect than rats that didnt receive the compound

Neither changes the 28-day window or the storage temperature

Zhang Z, Tang J, Song J, Xie M, Liu Y, Dong Z, Liu X, Li X, Zhang M, Chen Y, Shi H, Zhong J

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