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In addition, the transcription of the IGF-2 gene is similarly reduced by wild-type p53 (Zhang et al, 1996)
In muscle injury models, investigators typically examine biochemical and histological indicators of tissue remodeling, including inflammatory cell infiltration, collagen organization, and structural regeneration of muscle fibers
Saxena, D
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Recruitment for Phase III clinical trials to assess the efficacy and safety of bepirovirsen is also underway, with results expected in early 2026 (NCT05630807 and NCT05630820)
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