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Cell 2016
The key difference
It has been demonstrated that ligand-activated GLP- 1 receptor interacts with the Gas subunit and activates adenylate cyclase to generate cAMP
If you want needle-free GLP-1 with real efficacy evidence, it is currently the only option
Dangers: The misuse of these peptides, especially in higher-than-recommended doses or for extended periods, may pose risks
Additionally, although uncommon, reported cases of diabetic ketoacidosis (DKA) associated with GLP-1 RAs also warrant prompt treatment cessation (53)
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