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Published topical skin studies summarized by Schagen included one month of daily thigh application in 20 women, 12-week facial or eye-cream studies in 71 or 41 women, and a 12-week twice-daily Cu-GHK cream study in 67 women [2]
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Supplementation with Pycnogenol has been shown to have several beneficial effects on asthma and allergic rhinitis symptoms ( s anti-inflammatory effects are suggested to be responsible for its anti-allergic and anti-asthma efficacy
Quercetin, despite its strong antioxidant, anti-inflammatory, and antimicrobial activities 54 , suffers from poor solubility, low cutaneous absorption, and instability under physiological conditions 48,55,56
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