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A single co-formulated vial cannot hold all four components at matched exposures

2020;92: e20200012

Its sequence AcNlecyclo[AspHisDPheArgTrpLys]NH incorporates a norleucine substitution, a Dphenylalanine substitution, and a lactam bridge that cyclises the molecule, conferring markedly greater stability and resistance to enzymatic degradation than the native linear hormone

Two further washes were conducted with 1 ml ice-cold acetone

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