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A., Juvekar, A., Hu, H., Asara, J

During stress, the latent monomer of heat shock factor (HSF)-1 is rapidly converted to a trimeric form active in the nucleus to bind to the promoters of HSF-responsive heat shock genes and activate their transcription [94, 95]

Key Takeaways Hexarelin produces a larger absolute GH pulse than ipamorelin at equivalent molar doses in human studies, but co-stimulates cortisol and ACTH, which ipamorelin largely does not