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Since Tau is a critical microtubule-associated protein stabilising the neuronal cytoskeleton, its depletion indicates severe cytoskeletal destabilisation and axonal degeneration in the diabetic brain [42]

Incretin hormone action is regulated through specific receptors (GLP-1R and GIP-R)

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If any unusual reactions occur, discontinue use and seek professional medical advice

This observation has sparked clinical interest in whether GLP-1 and GIP receptor agonists like tirzepatide influence anxiety through mechanisms beyond appetite suppression and metabolic changes