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Pharmacovigilance studies indicate that GLP-1RAs, with the exception of albiglutide, demonstrate potential associations with pancreatic cancer risk, particularly evident in exenatide-treated patients who exhibit elevated cancer incidence rates
Serdiuk T, Fleischmann Y, Ghosh D, Delparente A, Reber V, Frey L, et al
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BATTLE OVER ANTI-OBESITY DRUGS The 68-week CagriSema clinical trial covered about 3,400 adults who had body mass indexes of at least 30, or at least 27 plus at least one weight-related condition such as hypertension or cardiovascular disease
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Literature reports of extracellular activity exist in various species, but genes that direct the enzymes to this compartment remain to be identified
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