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As a result, some patients may have been misclassified if PCOS was listed as a secondary or historical condition rather than an active clinical diagnosis

Human studies in this area are limited by small sample size and often nonrandomized character

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Although the TNF--initiated cachexic changes in C2C12 cells comprise a classic cell model of cancer cachexia, we consider that TNF-alpha is certainly not the only cytokine that is important for cancer cachexia