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Semaglutide roughly doubles the weight loss percentage of phentermine (13.7% versus 5-10%) over a much longer treatment duration
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When taken as prescribed, these drugs signal the brain that the stomach is full, reduce hunger, slow gastric emptying, and improve insulin sensitivity
May support evaluation Common Eligibility Factors BMI of 30 or greater BMI of 27 or greater with a related health condition Prior lifestyle efforts without durable results Ability to attend monitoring and report symptoms Willingness to support nutrition, movement, and maintenance Needs more review Reasons to Avoid, Delay, or Modify Treatment Pregnancy, planned pregnancy, or breastfeeding Personal or family history of medullary thyroid carcinoma or MEN2 for Wegovy/Zepbound Severe gastroparesis or significant gastrointestinal disease Active or unstable eating disorder Prior serious allergy to the medicine Inability to maintain fluid or nutrition Medication interactions or uncontrolled illness These medicines are not intended for cosmetic weight loss The goal is treatment of obesity or clinically significant overweight-related risknot rapid loss of a few pounds for an event
These medications are not over-the-counter supplements and should be used only under the guidance of a licensed healthcare provider
We recommend taking your thyroid medication on an empty stomach as usual, then waiting 30-60 minutes before eating or taking other medications
