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Early studies suggest good tolerance, but official dosing and long-term safety guidelines are still under evaluation

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Both selective AMYR agonists, and dual CTR and AMYR agonists such as sCT 5,6,7 , have demonstrated efficacy in controlling appetite and body weight, however this is not seen with a CTR-selective agonist 9

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This has resulted in the number of American adults taking GLP-1s increasing by 587% over the last five years