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The appetite suppression caused by tirzepatide can make it challenging to meet protein and micronutrient requirements, which is especially problematic for conditions where malnutrition worsens disease outcomes

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We found that oral administration of d-allulose induces GLP-1 release, activates vagal afferents, reduces food intake, and promotes glucose tolerance via enhanced insulin secretion and action

P = 0.0216) 72 h post 5FU treatment (Fig