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Gene ontology (GO) and pathway analysis were performed according to the standard enrichment computation method (17)

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10.1007/s00441-002-0562-7 Cell Tissue Res

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In this cells, the apoptotic pathway relied upon the same Trx1/p38MAPK/p53 signaling axis and cell survival to diamide relied upon redox activation of NE2FL2, in a way independent of Keap1 oxidation, but responsive to ERK1/2 activation (Filomeni et al., 2012)