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Inadequacy of macro-nutrients is just one cause of fatigue, and pumping yourself with Vitamin B12 shots will not help if the root cause is unrelated to B12 deficiency

B12 is water-soluble, and most of it is urinated out

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Hydroxyethyl starch inhibits glycocalyx-degrading enzymes, facilitating the restoration of glycocalyx thickness and enhancing expression of VE-cadherin, occludin, and zonula occludens-1, reducing albuminfluorescein isothiocyanate infiltration, and improving pulmonary vascular permeability [45]

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