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Development of composite PLGA microspheres containing exenatide-encapsulated lecithin nanoparticles for sustained drug release

Food and Drug Administration GIP: Glucose-dependent Insulinotropic Polypeptide GLP-1 RAs: Glucagon-like peptide-1 receptor agonists GQ: Grazing Questionnaire HR: Hazard Ratio LABS: Longitudinal Assessment of Bariatric Surgery PHQ-9: Patient Health Questionnaire-9 RCTs: Randomized Controlled Trials Rep(eat)-Q: Repetitive Eating Questionnaire RR: Risk Ratio SGLT2: Sodium-Glucose Cotransporter-2 Inhibitors SMD: Standardized Mean Difference STEP: Semaglutide Treatment Effect in People with obesity TOS: The Obesity Society USPSTF: U.S

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Mounjaro is linked to risks during pregnancy, including potential adverse effects on the fetus

That means Wegovy generally produces more weight loss, especially in people without diabetes

moreover, significant weight loss reduces the requirement for procedures, such as coronary artery bypass grafting, carotid endarterectomy, and percutaneous coronary intervention, as well as peripheral vascular disease, and total mortality by up to 24% [89, 90]