Course Highlights Discover how combining lifestyle modifications with GLP-1 receptor agonists can improve weight loss, glycemic control, and overall cardiometabolic health Examine the science behind GLP-1 receptor agonists, from their effects on insulin secretion and appetite regulation to next-generation agents like tirzepatide and orforglipron Learn best practices for patient education, dosing strategies, and interprofessional collaboration while addressing contraindications, adverse effects, and compounding warnings Introduction Obesity is a chronic and prevalent condition that impacts health, contributing to higher rates of morbidity and mortality
In health, GLP-1 stimulates the synthesis and secretion of insulin from pancreatic -cells in a glucose-dependent manner (i.e., it is activated when blood glucose levels are elevated, typically in the postprandial state)
This highlights the need for tailored treatment and careful monitoring
Five half-lives is the standard pharmacokinetic benchmark for clearing a drug from the system
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And they work, for some people
