Typical ALA dosing ranges from 300-600mg daily, often split into multiple doses due to its relatively short half-life
Its oral bioavailability is achieved through the incorporation of the absorption enhancer SNAC (N-[8-(2-hydroxybenzoyl)amino]octanoic acid), which works through two mechanisms: (1) temporarily raising the local pH in the stomach to reduce gastric protease activity
About four out of every 10 Americans are obese, according to the Centers for Disease Control and Prevention
Therefore, maintaining adequate levels of this crucial antioxidant is essential for promoting liver health and preventing conditions such as fatty liver disease
Present at millimolar concentrations in most mammalian cells, GSH is involved in virtually every aspect of cellular defence and metabolic regulation
Larder CE, Iskandar MM, Kubow S