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Physiological Reviews, 1983
Based on this, we studied whether the metabolic switch from mitochondrial OXPHOS to cytosolic aerobic glycolysis is required and/or sufficient for the immune activation seen in UQCR-C1 (and other OXPHOS complex) knockdown hemocytes
The benzyl alcohol preservative has been linked to severe toxicity in this population, including a potentially fatal condition known as gasping syndrome. Newborns have immature metabolic pathways and cannot efficiently metabolize benzyl alcohol, leading to its accumulation and metabolic acidosis with respiratory failure in severe cases
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