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This is one of the starkest parts of the story

Dull needles create jagged tears instead of clean channels, increasing inflammation without improving absorption

Each one is partially supported and each falls short

Structural modifications, including pegylation and glycosylation, enhance protein stability and prolong half-life, thereby improving therapeutic efficacy [285]

The injectable form was placed on the FDA's Category 2 bulk drug substances list in 2023, restricting compounding pharmacies from preparing it under Section 503A