The MC4 receptor plays a role in sexual function for both men and women, as evidenced by increased sexual desire observed when its activated
M., van Wietmarschen, H., Kremer, B
In women with PCOS, high concentrations of leptin have been reported to inhibit the expression of aromatase mRNA in granulosa cells, while the hyperandrogenic follicular environment in GCs was found to significantly reduce the expression of P450arom, which can convert androgens into estrogen, further increasing the levels of androgens and ultimately promoting follicular atresia (148150)
Microbiome and skin biology
Whats Included in a Medical Weight Loss Program
Filali-Mouncef Y, Hunter C, Roccio F, Zagkou S, Dupont N, Primard C, et al