severe diarrhea with tirzepatide after taking In a patient BMI 50 and prediabetes who has diarrhea on Tirzepatide Diarrhea: Causes & How

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Metformin and GLP-1 receptor agonists are often mentioned together in weight loss discussions, but they operate on completely different biological pathways

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This isnt a matter of vanity or trying to live up to an impossible ideal: for those who are affected, reducing weight by just 5-10% can improve risk factors and reduce the medical complications of obesity

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At the same time, preclinical and translational studies suggest potential direct or partially weight-independent effects of GLP1RAs on hepatocellular metabolism, inflammation, and the gut-liver axis [4]