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As such, we conclude that rs10305420 is probably the causal variant
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The serum ACE1 levels were increased in the LCLT and the placebo groups between days 1 and 21, however, this change reached statistical significance only for the LCLT group ( p = 0.029
Similarly, semaglutide ameliorates doxorubicin-induced cardiotoxicity by reducing BNIP3-mediated mitochondrial dysfunction through the PI3K/AKT pathway, enhancing mitochondrial function and reducing cardiac injury (Li et al., 2024), potentiating its clinical application in cardiovascular diseases
Loss of Angiotensin-Converting Enzyme-2 Exacerbates Diabetic Cardiovascular Complications and Leads to Systolic and Vascular Dysfunction: A Critical Role of the Angiotensin II/AT1 Receptor Axis
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