Additionally, rapid subcutaneous fluid volume expansion as the medication deposits can create pressure and temporary inflammation in the injection area
The American Gastroenterological Associations 2022 obesity pharmacotherapy guideline supports targeted rather than universal pretreatment lab screening
After verifying the results of the previous, highly controlled studies, the researchers expanded their study population to make it more reflective of HFpEF cases in clinical practice, finding that overall, the drugs were associated with a greater than 40% reduction in heart failure hospitalization or all-cause mortality as compared with sitagliptin
Make maintenance a primary goal
By week 12, cumulative weight loss of 56% of baseline body weight is common in clinical trials, though individual results vary
Numbness or tingling in the extremities that persists or worsens over time