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Cancer 91 , 17451751 (2001)
Knight, J., Wood, K
But experts emphasize that a thoughtful approach matters
It has been shown that HIV+ individuals have low levels of GSH
The preclinical effect sizes, while described as dramatic, may not have been judged sufficient to justify the financial risk of clinical trials
This includes upregulation of antioxidant enzymes (superoxide dismutase, catalase) that protect against oxidative damage, enhancement of growth factor expression (TGF-, VEGF, PDGF) that supports tissue repair, and suppression of inflammatory gene expression that contributes to chronic skin degradation
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