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It has been well-established that most mental disorders are caused by an interplay of a range of factors, including genetic, early developmental factors, environmental factors, and, in some cases, an initiating or precipitating factor (9, 10)

These small vesicles plays a major role in the formation of pre-metastatic niche by modifying distant organs (brain, liver, lung, etc.) and enhancing metastatic organotropism (124)

doi: 10.18502/ijrm.v23i1.18187 63 YuanXHFanYYYangCRGaoXRZhangLLHuYet al

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