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The proinflammatory mitochondrial phenotype is related to mtDNA mutation and decreased oxygen partial pressure in the synovium (Du et al., 2020), suggesting that hypoxia and oxidative stress may play a significant role in causing joint inflammation
Franois-Xavier Maquart Franois-Xavier Maquart is a researcher/professor at the Laboratory of Biochemistry, Faculty of Medicine, University of Reims, France, collaborating with Jacques-Paul Borel
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12 13 Table 1 Genes activated by NRF2
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