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Free radicals accumulate in the body due to oxidative stress, which can be caused by a number of different factors, including diet and lifestyle
For this reasons, several laboratories have developed EA analogues with improved properties
The authors concluded that GHK and GHK-Cu increased epidermal cell stemness and keratinocyte proliferation, also increasing p63 and integrin expression [ 48 , 49 ]
A tight control is needed to adjust each enzymatic step to the cellular requirements because the whole pathway consumes energy and produces toxic/reactive compounds, notably sulfite and sulfide
3) GSSG is reduced to GSH by NADPH (GR) as resumed in figure 3
The second way in which Glutathione helps in skin whitening is by halting the activation of Tyrosinase
