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Similarly, clear-cell carcinomas are rendered vulnerable to GPX4 inhibitors due to HIF-2-dependent polyunsaturated lipid accumulation 19
however, this theory has been called into question as APAP-protein adducts have been detected at 1 hour after APAP treatment, a time that that would precede GSH depletion
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doi: 10.1186/s40560-020-00453-4 122 HunterD
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