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The new glucagon-like peptide-1 (GLP-1) tablet is available to buy privately at some high-street and online pharmacies although it is not yet available on the NHS following the government's Medicines and Healthcare products Regulatory Agency approval of an oral version of semaglutide, the blockbuster drug better known under the brand names Wegovy and Ozempic
Its Phase 2 weight loss data (24.2% at 48 weeks) and mechanistic advantages in hepatic fat reduction through glucagon receptor activation suggest it could surpass semaglutide's efficacy if Phase 3 results confirm the Phase 2 findings
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While weight loss can occur without exercise, physical activity often leads to faster and more sustainable results
Mao X, Xu J, Wang W, Liang C, Hua J, Liu J, Zhang B, Meng Q, Yu X, Shi S
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