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doi:10.5021/ad.2016.28.4.438 Bobyntsev II, Chernysheva OI, Dolgintsev ME, Smakhtin MY, Belykh AE

In the GHK-Cu complex, the copper ion coordinates with multiple binding sites: the nitrogen from the histidine imidazole side chain, the alpha-amino group of glycine, the deprotonated amide nitrogen of the glycine-histidine peptide bond, and oxygen from the lysine carboxyl group, forming a square-planar pyramid configuration

The patients using both tend to be longevity-focused, productivity-oriented, and proactive about aging rather than reactive

The researchers further speculated that the peptide could have influenced umbilical vein endothelial cell proliferation (HUVECs)

No more scalp irritation, no heart palpitations when I accidentally used too much

Though GHK-Cu is naturally blue in color, topical products at concentrations typically used (up to 3%) are generally not noted to cause staining of the skin