The most important development for these two compounds specifically is that both were rejected by the FDA's Pharmacy Compounding Advisory Committee (PCAC) in late 2024
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Specifically, anti-LOX (36 mm), VED (35 mm), HCG (33 mm), LOX inhibitor and VED (39 mm), VED and HCG (34 mm), and LOX inhibitor + VED + HCG (38 mm) significantly lengthened the penis by 15% (5.0 mm), 8.0% (2.3 mm), 12% (4.0 mm), 26% (8.0 mm), 10% (3.2 mm), and 22% (7.0 mm), respectively
Heissigerova et al
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(1998) describe minimal cortisol and prolactin elevation compared to GHRP-2, GHRP-6, and hexarelin, a profile community sources commonly call the "cleanest GHRP." Clinical development was discontinued despite positive Phase II results