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Science 293 (5528), 293297
These systems achieve controlled drug release by modulating the physicochemical properties of polymers, such as solubility, release kinetics, and targeting capabilities, thereby enhancing therapeutic efficacy and reducing adverse effects ( 4.3.1 Basic polymeric nanocarrier systems Nanoparticle systems use polymeric nanoparticles as core carriers to effectively encapsulate drugs and deliver them to specific sites (e.g., joints and tumor regions) through passive or active targeting mechanisms (Zhao and Zhou, 2022)
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Conclusion In an intact rat brain, we determined the amount of glutamate as 78 fold higher relative to GABA and about two-fold relative to glutamine level with subtle variations in brain regions: hippocampus, cortex and cerebellum
TB-500 works at a broader systemic distance, using actin sequestration to drive cellular migration straight to the injury zone
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