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This sudden release can lead to suboptimal drug concentrations at the intended target site in the body, diminishing the drugs therapeutic effect [339]

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This is one of the most common questions I hear from clients right now, and the answer is more nuanced than a simple yes or no

It also remains in the body for up to one to two weeks after stopping, so you cant simply skip a dose and safely drink the same day

The pattern mirrors other side effects: worst during the first week at a new dose, gradual improvement over weeks 2 and 3, often resolution or significant improvement by week 4 at the same dose

Researchers should factor this into the study design