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Adverse events such as diarrhea, constipation, nausea, and vomiting associated with the GLP-1 RAs overlap with those seen with cancer treatments, so the patient who is undergoing treatment with an emetogenic regimen for cancer will likely experience additional weight loss, which can lead to nutritional deficiencies, loss of lean muscle mass, and loss of bone mass
In some patients, especially those with established retinopathy, a sharp metabolic improvement can briefly aggravate retinal findings before long-term benefit becomes clearer
J.CiceroL.BrooksT.HalleyH.RayS
Because of this necessary repair work, individuals with extreme insulin resistance may need to reach the 1.0 mg therapeutic dose or higher before seeing structural weight loss on the scale
FDA approval and clinical evidence Tesamorelin carries FDA approval under the brand name Egrifta, specifically for reducing excess visceral abdominal fat in HIV-positive patients with lipodystrophy
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