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These effects have been confirmed in animal experiments, but not in humans, and the specific mechanism remains unknown

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Notably, the hydroxyl group at the C4 position of the tetrahydropyran ring of substrate 7 also stabilizes the GSH-thiolate through an additional hydrogen bond (Extended Data Fig

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10.1016/j.freeradbiomed.2012.06.023 52 VanduchovaA.AnzenbacherP.AnzenbacherovaE

I pledge to discourage the public belittling of my colleagues, even when we do not agree