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However, very intense or prolonged training without adequate recovery may increase oxidative stress, increasing the demand for antioxidants like glutathione
201 A meta-analysis that reported findings from 23 randomized controlled trials involving 842 participants with stage 35 CKD indicated that probiotic, prebiotic, and synbiotic supplements improved creatinine and BUN levels, heightened markers of oxidative stress, reduced some markers of inflammation, and decreased uremic toxin levels
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