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In normal oxidative metabolism, the free radical formation is expected

There is an increased incidence of adenomas in patients with melanosis coli due to easier detection of adenomas against dark staining of colonic mucosa [6]

This peptide-metal complex can be endogenously generated in mammalian systems through proteolytic processing of larger precursor proteins

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[174] The analysis found that individuals using the medications had a slightly higher incidence of neovascular age-related macular degeneration compared to similar individuals not on the medications