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Gallbladder disease An increased risk of cholelithiasis and other gallbladder issues has been documented, presenting with fever and jaundice
Gastrointestinal effects Mounjaro makes food move more slowly through your digestive system, a process known as delayed gastric emptying
Hepatic glucagon receptor activation upregulates carnitine palmitoyltransferase 1 (CPT1), the rate-limiting enzyme that shuttles long-chain fatty acids across the outer mitochondrial membrane for -oxidation
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However, they carry risk of gastrointestinal side effects, pancreatitis risk (rare but serious), and thyroid concerns in animal studies
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