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Cost considerations Budget plays a practical role in this decision that deserves honest discussion

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These are not interchangeable in mechanism

Sustained weight loss could make dual GLP-1/GIP receptor agonists more attractive to payers, and increase the affordability of these drugs for healthcare systems

It activates multiple target receptor subtypes for broad systemic effects studied in preclinical models

Patient education and monitoring: Patients should receive clear guidance about distinguishing normal breathlessness during increased physical activity from concerning respiratory symptoms