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Several chemical conjugations such as azo linkage, indolequinone, trimethyl locked quinone and nitro-containing aromatic compounds are found to behave as hypoxia sensitive conjugations (Fig
Tanriverdi, G
reconstituted solutions should stay refrigerated, not refrozen
Considering the heterogeneity among ME/CFS patients, however, it is unlikely that one treatment will suit all ME/CFS patients
Yet, current literature lacks consensus on optimal intake levels, and comprehensive studies encompassing all polyphenol subclasses are still limited
The main limitations are GI side effects: nausea, constipation, and slowed gastric emptying
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