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Birnkrant et al 2018): Burns or major trauma (2472 hours post-injury) Neuromuscular disorders Myopathies Acute narrow-angle glaucoma or penetrating eye injury Side Effects Malignant Hypertheria Malignant hyperthermia (MH) is a rare, life-threatening autosomal dominant pharmacogenetic disorder of skeletal muscle that is triggered by exposure to volatile inhalational anesthetics (e.g., sevoflurane, isoflurane, desflurane) and/or succinylcholine in genetically susceptible individuals (Ndikontar et al., 2020

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One-step cleavage of all acid-labile groups with excess of trifluoroacetic acid (TFA) yielded the tris-trifluoroacetate salt of deprotected linear hexapeptide 11 with all prerequisites for cyclization

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Libraries were prepared using the Universal Plus mRNA-seq protocol (Tecan) according to the manufacturers protocol

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