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Circulation 2018;138:1537-50.ArticlePubMedPMC 42

Muscle and joint complaints Tirzepatide muscle pain and body aches are reported by a subset of users, and these may recur or change in character when switching between medications

These presumed changes in BMI over time are not accounted for in this dataset but would likely increase the odds ratio of the effect of BMI on lymphedema risk based on what has been previously published

Recent studies have found that for postmenopausal women taking a GLP-1, the addition of hormone therapy can amplify weight loss, leading to a bigger reduction in weight than you'd get from taking a GLP-1 alone

This means retatrutide can directly target liver fat in a way that other medications can't