Applications in Research: Observations from preclinical and clinical literature
The Journal of Steroid Biochemistry and Molecular Biology
Key Benefits and Actions Supports a healthy seasonal histamine response, outdoors and indoors Provides nutrients needed to support healthy hist
In one mouse study, researchers found that the peptide reduced the pain felt by the animals in their paws when placed on a mildly hot plate. The authors explained that this could be because GHK is similar in structure to cimetidine, a histamine H2 receptor antagonist sometimes given to reduce pain in certain digestive conditions.3 10 In rodents, doses as low as 0.5mg/kg were found to be effective in delivering these anti-pain effects.25 In a 70kg human, an equivalent dose would be around 5.6mg, though thats likely higher than necessary: pharmaceutical-grade GHK-Cu normally ranges from 0.5 mg to 2.5mg per injection
Mechanism of Action BPC-157: Acts by promoting angiogenesis, stimulating growth factor production, and activating pathways crucial for cell migration and repair, such as the FAK-paxillin axis
Gord Kerr Author Gordon Kerr is a retired nutrition professional with more than 15 years of experience in the healthcare industry